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PENTASA® FORMULATIONS

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PENTASA® FORMULATIONS

PENTASA® has a range of oral and rectal formulations for achieving and maintaining remission in mild to moderate Ulcerative Colitis1-7

High dose* once-daily dosing provides a simple route to remission1-11

The range of oral and rectal formulations shown below can be used in adults.
For guidance on the use of Pentasa® in paediatrics click here.

ORAL FORMULATIONS1-5

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4g sachet
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2g sachet
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1g sachet
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1g tablet
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500mg tablet

RECTAL FORMULATIONS6-7

4g-sachets-web
1g enema
4g-sachets-web
1g suppository

Images do not show medication at actual size.

Once-daily dosing is likely to improve convenience & adherence13

ACHIEVING REMISSION:
Doses-for-Remission-2-4g

1 x 4g PENTASA® sachet5

4 x 1g PENTASA® tablets2

PENTASA® tablets can be dispersed in cold water to facilitate swallowing12

MAINTAINING REMISSION:
Doses-for-Remission-2-4g

1 x 2g PENTASA® sachet4

2 x 1g PENTASA® tablets2

All Rectal preparations are Once Daily

RECTAL PREPARATIONS:
Doses-for-Remission-2-4g

1g PENTASA® enema treating left-sided disease6

1g PENTASA® suppository for treating proctitis7

Images do not show medication at actual size.

HOW TO TAKE PENTASA®

PENTASA® can be taken in a variety of forms to suit patient needs

HOW TO TAKE PENTASA® ORALLY:

500mg-tablets-web

Open the PENTASA sachet with care.

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Empty the contents into either a yoghurt or yoghurt drink and consume immediately.

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Empty the contents of the sachet on to the tongue.

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Wash down with water or orange juice.

HOW TO USE THE PENTASA® ENEMA:

  • Immediately before use, take the enema bottle out of the aluminium foil pack and then shake well
  • To break the seal twist the nozzle clockwise one full turn (the nozzle should then be in the same direction as before turning)
  • Put your hand in one of the disposal bags provided in the pack
  • Wrap this hand around the enema bottle
  • To administer the enema, lie on your left side with the left leg straight and the right leg bent forward for balance. The bottle content should be applied within a maximum of 30-40 seconds
  • Once the bottle is empty, withdraw the tip with the bottle still compressed
  • The enema should be retained in the administration position for 5-10 minutes until the urge to pass the enema has disappeared
  • Roll the plastic disposal bag over the empty bottle, discard it and then wash your hands

 

 

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HOW TO USE THE PENTASA® SUPPOSITORY:

 

You should make sure that you empty your bowels before inserting the suppository

  • Tear along the perforation to remove one suppository blister from a blister strip
  • Put a protector on the finger with which you will insert the suppository
  • Remove the suppository from the blister before insertion, this is done by pushing the suppository through the printed foil
  • Insertion may be easier if you moisten the suppository with water first
  • Insert the suppository gently and fully into the back passage, it may help to lie down on one side and raise the other knee
  • Remain still for a few minutes after insertion to help keep the suppository in place. If it comes out within 10 minutes, a new one should be inserted
  • Dispose of the empty blister and used finger protector safely and wash your hands
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  • Pentasa Slow Release Tablets 500 mg. SmPC.
  • Pentasa Slow Release Tablets 1 g. SmPC.
  • Pentasa Sachet 1 g. SmPC.
  • Pentasa Sachet 2 g. SmPC.
  • Pentasa Sachet 4 g. SmPC.
  • Pentasa Enema 1 g. SmPC.
  • Pentasa Suppositories 1 g. SmPC.
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Job Code: UK-PA-2400044 - Date of preparation: November 2024

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