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The following oral PENTASA® formulations are licensed for achieving and maintaining remission in children from the age of 6 and upwards: 1-5
1g sachet
2g sachet
4g sachet
500mg tablet
1g tablet
*All PENTASA® oral presentations are licensed for children from six years of age and given in divided doses.
Active:
Starting – give 30-50mg per kg per day in divided doses.
Maximum dose = 75mg per kg per day in divided doses.
Total dose not to exceed 4g per day.
MAINTENANCE:
Starting – give 15-30mg per kg per day in divided doses.
Total dose not to exceed 2g per day.
Sachets can be incorporated into yoghurt or washed down with water or orange juice3-5
Granules can be washed down with water or orange juice3-5
Tablets can be broken1
Tablets can be dispersed in 50ml of cold water1,2
It doesn’t need to be taken at meal times because PENTASA®’s unique ethyl cellulose coated microgranules release mesalazine at all enteral pH conditions, independent of food co-administration1-17
Delivery is only slightly affected by diarrhoea1-5
Job Code: UK-PA-2400044 - Date of preparation: November 2024